Congratulations to Gao Zhiyuan, Jia Shaorui, their paper entitled 'An Activatable Near-Infrared Afterglow Theranostic Prodrug with Self-Sustainable Magnification Effect of Immunogenic Cell Death' has been published in Angew. Chem. Int. Ed.-Prof.Ding’s Research Group

Congratulations to Gao Zhiyuan, Jia Shaorui, their paper entitled 'An Activatable Near-Infrared Afterglow Theranostic Prodrug with Self-Sustainable Magnification Effect of Immunogenic Cell Death' has been published in Angew. Chem. Int. Ed.

2022-08-02

Abstract
We report a theranostic prodrug that could self-report the drug release, immunogenic cell death (ICD) progression, and cold-to-hot tumor transformation with activated near-infrared afterglow chemiluminescence. Such an intelligent prodrug also shows a unique self-sustainable ICD magnification effect, completely eradicating the existing tumor and preventing further tumor recurrence through enhanced antitumor immune response.

Angewandte Chemie International Edition. (IF 16.823) DOI: 10.1002/anie.202209793